产品展厅
产品展厅
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, M | ELISA, ICC | M | Purified | Monoclonal Antibody |
| Description | |
|---|---|
| Catalogue Number | MAB4388 |
| Brand Family |
Chemicon® |
| Trade Name |
|
| Description | Mouse Anti-Stella Antibody |
| Background Information | Stella is specifically expressed by oocytes, pluripotent cells and primordial germ cells at the time of their emergence in gastrulating embryos, and is an important maternal factor in the cleavage stages of mouse embryos (Bortvin, 2004). The requirement for stella in germ cell specification remains controversial, however, most embryos from stella deficient mice failed to develop normally and rarely reach the blastocyst stage (Bortvin, 2004; Payer, 2003). The stella gene encodes a protein with an SAP-like domain and splicing factor motif-like structure, suggesting possible roles in chromosomal organization and RNA processing (Payer, 2003). |
| Product Information | |
|---|---|
| Format | Purified |
| Presentation | Purified Ascites presented as a liquid in 0.02M phosphate buffer, 0.25M NaCI, pH 7.6 with 0.1% sodium azide. |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Mouse Anti-Stella Antibody detects level of Stella & has been published & validated for use in ELISA & IC. |
| Key Applications |
|
| Biological Information | |
|---|---|
| Clone | 3H5.2 |
| Concentration | Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Host | Mouse |
| Specificity | Reacts with stella from human and mouse. |
| Isotype | IgG1 |
| Species Reactivity |
|
| Antibody Type | Monoclonal Antibody |
| Entrez Gene Number |
|
| Entrez Gene Summary | This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X. |
| Gene Symbol |
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| UniProt Number |
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| UniProt Summary |
FUNCTION: SwissProt: Q6W0C5 # May play a role in maintaining cell pluripotentiality. SIZE: 159 amino acids; 17851 Da SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm (By similarity). TISSUE SPECIFICITY: Low expression in testis, ovary and thymus. Expressed in embryonic stem and carcinoma cells. Highly expressed in testicular germ cell tumors. DEVELOPMENTAL STAGE: Expressed in fetal ovary. |
| Stem Cell Type |
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| Product Usage Statements | |
|---|---|
| Usage Statement |
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| Storage and Shipping Information | |
|---|---|
| Storage Conditions | Maintain refrigerated at 2-8C in undiluted aliquots for up to 12 months. |
| Packaging Information | |
|---|---|
| Material Size | 100 μg |
